LymphedemaV1, France, Analysis, bibRecord, 000116

Lymphatic collecting vessel maturation and valve morphogenesis.

Identifieur interne : 000116 ( France/Analysis ); précédent : 000115; suivant : 000117

Lymphatic collecting vessel maturation and valve morphogenesis.

Auteurs : Daniel Vittet [France]

Source :

Microvascular research [ 1095-9319 ] ; 2014.

RBID : pubmed:25020266

Descripteurs français

KwdFr :
- Animaux, Lymphangiogenèse (physiologie), Lymphoedème, Modèles biologiques, Morphogenèse (physiologie), Plan d'organisation du corps, Souris, Transduction du signal, Vaisseaux lymphatiques (embryologie), Vaisseaux lymphatiques (métabolisme).
MESH :
- embryologie : Vaisseaux lymphatiques.
- métabolisme : Vaisseaux lymphatiques.
- physiologie : Lymphangiogenèse, Morphogenèse.
- Animaux, Lymphoedème, Modèles biologiques, Plan d'organisation du corps, Souris, Transduction du signal.

English descriptors

KwdEn :
- Animals, Body Patterning, Lymphangiogenesis (physiology), Lymphatic Vessels (embryology), Lymphatic Vessels (metabolism), Lymphedema, Mice, Models, Biological, Morphogenesis (physiology), Signal Transduction.
MESH :
- embryology : Lymphatic Vessels.
- metabolism : Lymphatic Vessels.
- physiology : Lymphangiogenesis, Morphogenesis.
- Animals, Body Patterning, Lymphedema, Mice, Models, Biological, Signal Transduction.

Abstract

The lymphatic vasculature plays an essential role in the maintenance of tissue interstitial fluid balance and in the immune response. After capture of fluids, proteins and antigens by lymphatic capillaries, lymphatic collecting vessels ensure lymph transport. An important component to avoid lymph backflow and to allow a unidirectional flow is the presence of intraluminal valves. Defects in the function of collecting vessels lead to lymphedema. Several important factors and signaling pathways involved in lymphatic collecting vessel maturation and valve morphogenesis have now been discovered. The present review summarizes the current knowledge about the key steps of lymphatic collecting vessel development and maturation and focuses on the regulatory mechanisms involved in lymphatic valve formation.

DOI: 10.1016/j.mvr.2014.07.001
PubMed: 25020266

Affiliations:

France

Links to Exploration step

pubmed:25020266

Le document en format XML

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<affiliation wicri:level="1"><nlm:affiliation>Inserm, U1036, Grenoble, F-38000 France, CEA, DSV, iRTSV, Laboratoire Biologie du Cancer et de l'Infection, Grenoble, F-38000 France, Univ Grenoble Alpes, Grenoble, F-38000 France. Electronic address: daniel.vittet@cea.fr.</nlm:affiliation>
<country wicri:rule="zip">France</country>
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<affiliation wicri:level="1"><nlm:affiliation>Inserm, U1036, Grenoble, F-38000 France, CEA, DSV, iRTSV, Laboratoire Biologie du Cancer et de l'Infection, Grenoble, F-38000 France, Univ Grenoble Alpes, Grenoble, F-38000 France. Electronic address: daniel.vittet@cea.fr.</nlm:affiliation>
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<series><title level="j">Microvascular research</title>
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<term>Lymphatic Vessels (metabolism)</term>
<term>Lymphedema</term>
<term>Mice</term>
<term>Models, Biological</term>
<term>Morphogenesis (physiology)</term>
<term>Signal Transduction</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Lymphangiogenèse (physiologie)</term>
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<term>Modèles biologiques</term>
<term>Morphogenèse (physiologie)</term>
<term>Plan d'organisation du corps</term>
<term>Souris</term>
<term>Transduction du signal</term>
<term>Vaisseaux lymphatiques (embryologie)</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lymphatic Vessels</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Vaisseaux lymphatiques</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Lymphangiogenèse</term>
<term>Morphogenèse</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Lymphangiogenesis</term>
<term>Morphogenesis</term>
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<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Body Patterning</term>
<term>Lymphedema</term>
<term>Mice</term>
<term>Models, Biological</term>
<term>Signal Transduction</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Lymphoedème</term>
<term>Modèles biologiques</term>
<term>Plan d'organisation du corps</term>
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<front><div type="abstract" xml:lang="en">The lymphatic vasculature plays an essential role in the maintenance of tissue interstitial fluid balance and in the immune response. After capture of fluids, proteins and antigens by lymphatic capillaries, lymphatic collecting vessels ensure lymph transport. An important component to avoid lymph backflow and to allow a unidirectional flow is the presence of intraluminal valves. Defects in the function of collecting vessels lead to lymphedema. Several important factors and signaling pathways involved in lymphatic collecting vessel maturation and valve morphogenesis have now been discovered. The present review summarizes the current knowledge about the key steps of lymphatic collecting vessel development and maturation and focuses on the regulatory mechanisms involved in lymphatic valve formation.</div>
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Serveur d'exploration sur le lymphœdème

Lymphatic collecting vessel maturation and valve morphogenesis.

Lymphatic collecting vessel maturation and valve morphogenesis.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.